Anti-RPL3 antibody produced in rabbit
SIGMA/AV48157 - affinity isolated antibody
Synonym: Anti-MGC104284; Anti-Ribosomal protein L3; Anti-TARBP-B
Product Type: Chemical
Immunoblotting Cell Type: 721_B (Cat. No. AV48157). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type 721_B
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 40 kDa |
| NCBI accession no. | XP_001718487   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, bovine, rabbit, guinea pig, horse, human, dog, mouse |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | B3KS36 |
| Application: | Rabbit Anti-RPL3 antibody is suitable for western blot applications at a concentration of 1μg/ml. |
| Biochem/physiol Actions: | Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL3 is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation.Ribosomes |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Ribosomal protein L3 is a cytoplasmic protein that can bind to HIV-1 TAR mRNA and modulated transactivation mediated by Tat. Studies have reported that the autoregulatory circuit of RPL3 required KHSRO, NPM and H1 proteins. RPL3 gene is also known to be overexpressed in obesity models. Rabbit Anti-RPL3 antibody recognizes human, mouse, rat, zebrafish, chicken, pig, and bovine RPL3. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human RPL3 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: YHHRTEINKKIYKIGQGYLIKDGKL |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |