Anti-TPM2 antibody produced in rabbit
SIGMA/AV48224 - IgG fraction of antiserum
Synonym: Anti-AMCD1; Anti-DA1; Anti-TMSB; Anti-TropoMyosin 2 (β)
Product Type: Chemical
Immunohistochemistry Anti-TPM2: Cat. No. AV48224: Immunohistochemistry of TPM2 in Human Muscle tissue with TPM2 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV48224). Lanes 1. Antibody dilution (concentration) 2.5 μg/mL in cell type HepG2
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 33 kDa |
| NCBI accession no. | NP_003280   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rabbit, dog, rat, mouse, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P07951 |
| Application: | Rabbit anti-TPM2 antibodies have been used for immunoblot analysis. It is also suitable for IHC applications at a concentration of 4-8 μg/ml. |
| Biochem/physiol Actions: | TPM2 is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers.The TPM2 gene encodes beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers (Tajsharghi et al., 2007 [PubMed 17846275]). See also TPM1 (MIM 191010), TPM3 (MIM 191030), and TPM4 (MIM 600317).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | TPM2 codes for beta-tropomyosin that belongs to the actin binding protein family. Mutations in TPM2 have been linked to congenital myopathies, Sheldon-Hall syndrome and cap disease. Rabbit anti-TPM2 antibody recognizes canine, bovine, rabbit, zebrafish, chicken, human, mouse, and rat TPM2 |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human TPM2 |
| Other Notes: | Synthetic peptide located within the following region: AETRAEFAERSVAKLEKTIDDLEDE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |