Anti-GNB2 antibody produced in rabbit
SIGMA/AV48278 - affinity isolated antibody
Synonym: Anti-Guanine nucleotide binding protein (G protein), β polypeptide 2
Product Type: Chemical
Immunoblotting Cell Type: fetal brain (Cat. No. AV48278). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type fetal brain
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 37 kDa |
| NCBI accession no. | NP_005264   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, dog, bovine, mouse, rabbit, guinea pig, human, horse |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | P62879 |
| Application: | Rabbit anti-GNB2 antibody is suitable for western blot applications at a concentration of 1μg/ml. |
| Biochem/physiol Actions: | Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. GNB2 is a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5′ UTR. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | GNB2 encodes the β subunit of the heterotrimeric guanine nucleotide-binding protein. It modulates α subunits of the heterotrimer. It also regulates signaling receptors and effectors. Rabbit anti-GNB2 antibody recognizes bovine, human, mouse, rat, zebrafish, and canine GNB2. |
| Immunogen: | Synthetic peptide directed towards the middle region of human GNB2 |
| Other Notes: | Synthetic peptide located within the following region: CCRFLDDNQIITSSGDTTCALWDIE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |