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Anti-TRMU antibody produced in rabbit

SIGMA/AV48819 - affinity isolated antibody

Synonym: Anti-MGC99627; Anti-MTO2; Anti-MTU1; Anti-TRMT; Anti-TRMT1; Anti-TRNT1; Anti-tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-AV48819-100UL 100 µL
$580.00
1/EA
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Immunoblotting Cell Type: HeLa (Cat. No. AV48819). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type HeLa

 

antibody form affinity isolated antibody
antibody product type primary antibodies
biological source rabbit
clone polyclonal
concentration 0.5 mg - 1 mg/mL
conjugate unconjugated
form buffered aqueous solution
mol wt 48 kDa
NCBI accession no. NP_060476 
Quality Level 100 
shipped in wet ice
species reactivity mouse, human, rat, bovine, guinea pig, rabbit
storage temp. −20°C
target post-translational modification unmodified
technique(s) western blot: suitable
UniProt accession no. O75648 
Application: Rabbit Anti-TRMU antibody is suitable for western blot applications at a concentration of 1μg/ml.
Biochem/physiol Actions: TRMU is a member of the trmU family. It is a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.
Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description: TRMU codes for tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase that catalyzes the 2-thiolation of uridine. Studies have reported that TRMU mutations affect the deafness-associated mutations in 12S ribosomal RNA.
Rabbit Anti-TRMU antibody recognizes bovine, canine, human, mouse, and rat TRMU.
Immunogen: Synthetic peptide directed towards the C terminal region of human TRMU
Other Notes: Synthetic peptide located within the following region: ALATGQFAVFYKGDECLGSGKILRLGPSAYTLQKGQRRAGMATESPSDSP
Physical form: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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