Anti-RB1CC1 antibody produced in rabbit
SIGMA/AV50467 - affinity isolated antibody
Synonym: Anti-CC1; Anti-DRAGOU14; Anti-FIP200; Anti-RB1-inducible coiled-coil 1
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 183 kDa |
NCBI accession no. | NP_001077086 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | bovine, dog, human, rat, mouse, guinea pig, horse |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | immunohistochemistry: suitable |
western blot: suitable | |
UniProt accession no. | Q8TDY2 |
Application: | Anti-RB1CC1 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml. |
Biochem/physiol Actions: | RB1-inducible coiled-coil 1 (RB1CC1; ATG17) enhances the expression of retinoblastoma 1 gene in cancer cells. It coordinates with signaling pathways involved in cell growth, proliferation, apoptosis and migration. RB1CC1 exhibits tumor-suppressive functions in prostate cancer cells. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the C terminal region of human RB1CC1 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: SGASRRPWVLGKVMEKEYCQAKKAQ |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |