Anti-SHC1 antibody produced in rabbit
SIGMA/AV50490 - affinity isolated antibody
Synonym: Anti-FLJ26504; Anti-SHC; Anti-SHC (Src homology 2 domain containing) transforming protein 1; Anti-SHCA; Anti-p52SHC; Anti-p66; Anti-p66SHC
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 52 kDa |
NCBI accession no. | NP_892113 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | mouse, guinea pig, horse, dog, human, bovine, rat, rabbit |
storage temp. | −20°C |
technique(s) | western blot: suitable |
UniProt accession no. | P29353 |
Application: | Anti-SHC1 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml. |
Biochem/physiol Actions: | Src homology 2 domain containing) transforming protein 1 (SHC1; SHC; SHCA) gene encodes three isoforms, p66Shc, p52Shc and p46Shc. p52Shc and p46Shc are involved recruitment of Grb2/Sos complex and activation of Ras pathway. p66Shc is involved in regulating the effects of reactive oxygen species and aging. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the C terminal region of human SHC1 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: AEQLRGEPWFHGKLSRREAEALLQL |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |