Anti-ING1 antibody produced in rabbit
SIGMA/AV50512 - IgG fraction of antiserum
Synonym: Anti-Inhibitor of growth family, member 1; Anti-p24ING1c; Anti-p33; Anti-p33ING1; Anti-p33ING1b; Anti-p47; Anti-p47ING1a
Product Type: Chemical
antibody form | IgG fraction of antiserum |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 32 kDa |
NCBI accession no. | NP_005528 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | dog, human, guinea pig, bovine, rat, mouse |
storage temp. | −20°C |
technique(s) | western blot: suitable |
UniProt accession no. | Q5T9H0 |
Application: | Anti-ING1 antibody produced in rabbit is suitable for western blotting at a concentration of 2.5μg/ml. |
Biochem/physiol Actions: | Inhibitor of growth family, member 1 (ING1; p47; p33) is a nuclear protein with tumor suppressor activity. It interacts with p53, participates in p53-mediated signaling and regulates cell growth and apoptosis. However, ING1 also acts independent of p53; translocates to mitochondria and induces apoptosis by altering mitochondrial membrane potential. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Immunogen: | Synthetic peptide directed towards the C terminal region of human ING1 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: EKKAKTSKKKKRSKAKAEREASPAD |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |