Anti-JPH2 antibody produced in rabbit
SIGMA/AV51358 - affinity isolated antibody
Synonym: Anti-FLJ40969; Anti-JP-2; Anti-JP2; Anti-Junctophilin 2
Product Type: Chemical
Immunoblotting Cell Type: fetal muscle (Cat. No. AV51358). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type fetal muscle
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 74 kDa |
| NCBI accession no. | NP_065166   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | dog, human, horse, guinea pig, bovine, rat, mouse |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9BR39 |
| Application: | Anti-JPH2 antibody produced in rabbit is suitable for western blotting at a concentration of 2.5 μg/ml. |
| Biochem/physiol Actions: | Junctophilin 2 (JPH2; CMH17) is a member of the junctophilin family. The members of this family form the junctional complexes present between the plasma membrane and the endoplasmic/sarcoplasmic reticululm. JPH2 couples the sarcolemmal and the intracellular calcium channels in the skeletal and cardiac muscle. The expression of JPH2 is essential for the formation of postnatal T-tubule in mammals. Dysregulation of junctophilins result in a variety of cardiac disorders. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human JPH2 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: ANQESNIARTLARELAPDFYQPGPE |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |