Anti-AP1G1 antibody produced in rabbit
SIGMA/AV51923 - affinity isolated antibody
Synonym: Anti-ADTG; Anti-Adaptor-related protein complex 1, γ1 subunit; Anti-CLAPG1; Anti-MGC18255
Product Type: Chemical
Immunoblotting Cell Type: fetal brain (Cat. No. AV51923). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type fetal brain
Western Blotting Western Blot of AP1G1 in Human HepG2 with AP1G1 antibody at 1 μg/mL
Western Blotting Western Blot of AP1G1 in Human Jurkat with AP1G1 antibody at 1 μg/mL
Western Blotting Western Blot of AP1G1 in Human Adult Placenta with AP1G1 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 91 kDa |
| NCBI accession no. | NP_001119   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, horse, dog, pig, mouse, rabbit |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | O43747 |
| Biochem/physiol Actions: | Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. AP1G1 is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family.Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human AP1G1 |
| Other Notes: | Synthetic peptide located within the following region: DHMRSALLERMPVMEKVTTNGPTEI |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |