Anti-ST6GALNAC2 antibody produced in rabbit
SIGMA/AV53653 - affinity isolated antibody
Synonym: Anti-SIAT7; Anti-SIAT7B; Anti-SIATL1; Anti-ST6 -
Product Type: Chemical
Immunoblotting Cell Type: fetal heart (Cat. No. AV53653). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type fetal heart
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 42 kDa |
| NCBI accession no. | NP_006447   |
| shipped in | wet ice |
| species reactivity | human, horse, rat, rabbit, pig |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9UJ37 |
| Application: | Anti-ST6GALNAC2 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL. |
| Biochem/physiol Actions: | ST6GALNAC2 is primarily expressed in skeletal muscle, heart, kidney, placenta, lung and leukocytes. Overexpression of ST6GALNAC2 abolishes the cell surface HECA-452/CLA expression, reduces the number of rolling leukocytes on P- and L-selectin-bearing substrates as well as enhances the median rolling velocity of remaining cells during the synthesis of the leukocyte selectin ligand on human P-selectin glycoprotein ligand-1. Increased expression of the sialyltransferase ST6GalNAc-II indirectly reduces the galactosylation of the O-glycan substrate. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | ST6 (alpha-N-acetyl-neuraminy |
| Immunogen: | Synthetic peptide directed towards the middle region of human ST6GALNAC2 |
| Other Notes: | Synthetic peptide located within the following region: VNTMKNSLVSYWNLGFTSVPQGQDL |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |