Anti-ERCC5 antibody produced in rabbit
SIGMA/AV54287 - affinity isolated antibody
Synonym: Anti-COFS3; Anti-ERCM2; Anti-Excision repair cross-complementing rodent repair deficiency, group 5; Anti-UVDR; Anti-XPG; Anti-XPGC
Product Type: Chemical
Immunoblotting Cell Type: fetal brain (Cat. No. AV54287). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type fetal brain
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 133 kDa |
| NCBI accession no. | NP_000114   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human, rabbit, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | P28715 |
| Application: | Anti-ERCC5 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL |
| Biochem/physiol Actions: | Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human ERCC5 |
| Other Notes: | Synthetic peptide located within the following region: NPQAIDIESEDFSSLPPEVKHEILT |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |