Anti-ACADVL antibody produced in rabbit
SIGMA/AV54486 - affinity isolated antibody
Synonym: Anti-ACAD6; Anti-Acyl-coenzyme A dehydrogenase, very long chain; Anti-LCACD; Anti-VLCAD
Product Type: Chemical
Immunohistochemistry ACADVL Antibody: Cat. No. AV54486: Immunohistochemistry analysis of ACADVL in Human Pineal Tissue with ACADVL Antibody 5.0 μg/mL. Observed Staining: Cytoplasmic in cell bodies of pinealocytes
Immunoblotting Cell Type: HepG2 (Cat. No. AV54486). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type HepG2
Immunoblotting ACADVL: Cat. No. AV54486: Western blot analysis of ACADVL in Human Adult Placenta cell lysates with ACADVL antibody at 1.0 μg/mL.
Immunoblotting ACADVL: Cat. No. AV54486: Western blot analysis of ACADVL in Human HeLa cell lysates with ACADVL antibody at 1.0 μg/mL.
Immunoblotting ACADVL: Cat. No. AV54486: Western blot analysis of ACADVL in Human Fetal Muscle cell lysates with ACADVL antibody at 1.0 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 64 kDa |
| NCBI accession no. | NP_001029031   |
| shipped in | wet ice |
| species reactivity | horse, dog, rat, pig, bovine, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P49748 |
| Application: | Anti-ACADVL antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL. |
| Biochem/physiol Actions: | The protein encoded by ACADVL (Acyl-coenzyme A dehydrogenase, very long chain) gene belongs to acyl-CoA dehydrogenases (ACADs) family and is specific to esters of long-chain and very long chain fatty acids like-palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. It is a homodimer of 67kDa subunits located in mitochondrion inner membrane, where it catalyzes the initial, rate-limiting step of mitochondrial fatty acid β-oxidation. Missense mutations in ACADVL gene may leads to partial carnitine palmitoyltransferase II deficiency. Deficiency of the encoded protein reduces myocardial fatty acid β-oxidation and results in hypertrophic cardiomyopathy. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human ACADVL |
| Other Notes: | Synthetic peptide located within the following region: RPYAGGAAQESKSFAVGMFKGQLTT |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |