Anti-UBE4B antibody produced in rabbit
SIGMA/AV54552 - affinity isolated antibody
Synonym: Anti-E4; Anti-HDNB1; Anti-KIAA0684; Anti-UBOX3; Anti-UFD2; Anti-Ubiquitination factor E4B (UFD2 homolog, yeast)
Product Type: Chemical
Immunoblotting Cell Type: fetal brain (Cat. No. AV54552). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type fetal brain
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 146 kDa |
| NCBI accession no. | NP_001099032   |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | O95155 |
| Application: | Anti-UBE4B antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL. |
| Biochem/physiol Actions: | UBE4B gene, located on chromosome 1p36, encodes a conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is one of the strongest neuroblastoma tumor suppressor genes. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human UBE4B |
| Other Notes: | Synthetic peptide located within the following region: SPMFCSVASFGASSLSSLYESSPAP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |