Anti-GLE1 antibody produced in rabbit
SIGMA/AV54579 - affinity isolated antibody
Synonym: Anti-GLE1 RNA export mediator homolog (yeast); Anti-GLE1L; Anti-hGLE1
Product Type: Chemical
Immunoblotting Cell Type: placenta (Cat. No. AV54579). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type placenta
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 75 kDa |
| NCBI accession no. | NP_001003722   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, horse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q53GS7 |
| Application: | Anti-GLE1 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL. |
| Biochem/physiol Actions: | GLE1 is required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. It may be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC). Mutations in GLE1 result in a fetal motoneuron disease. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human GLE1 |
| Other Notes: | Synthetic peptide located within the following region: LKLREAEQQRVKQAEQERLRKEEGQ |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |