5-Bromo-2′-deoxyuridine 5′-triphosphate sodium salt
SIGMA/B0631 - ≥90%
Synonym: 5-BrdUTP
CAS Number: 102212-99-7
Empirical Formula (Hill Notation): C9H14BrN2O14P3
Molecular Weight: 547.04
MDL Number: MFCD00057405
Linear Formula: C9H14BrN2O14P3
Product Type: Chemical
| assay | ≥90% |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C9H14BrN2O14P3.Na.H/c1 |
| InChI key | UWZGQOWZUSBZMC-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | [Na].OC1CC(OC1COP(O)(=O)O |
| solubility | water: 50 mg/mL, clear, colorless to faintly yellow |
| storage temp. | −20°C |
| Application: | 5-Bromo-2′-deoxyuridine 5′-triphosphate (5-BrdUTP) may be used as a labeling TdT substrate for terminal deoxynucleotidyl transferase (TdT) reactions or for DNA synthesis. BrdUTP is also used as an effective mutagenic agent. 5-BrdUTP labeling may be detected by immunological techniques or 5-BrdUTP may be derivitized by biotinylation or other methods for detection by fluorogenic or chromogenic methods. |
| Application: | 5-Bromo-2′-deoxyuridine 5′-triphosphate sodium salt has been used: • in the labelling of 3′-OH termini of fragmented DNA with double stranded breaks in african green monkey kidney cells • to label cleaved DNA ends in apoptosis assay in avian tissue sections • for incorporation into mice prostates for immunohistochemistry studies |
| General description: | 5-Bromo-2′-deoxyuridine 5′-triphosphate is used for incorporation into DNA for studying normal and tumor cell proliferation profiles. |
| Packaging: | 1, 5 mg in glass bottle |
| Packaging: | 25 mg in poly bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | ≥90% |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |


