Cibacron Blue 3G-A
SIGMA/B1064 - Dye content ≥55 %
Synonym: Cibacron Blue; 1-
CAS Number: 84166-13-2
Empirical Formula (Hill Notation): C29H20ClN7O11S3
Molecular Weight: 774.16
MDL Number: MFCD30607256
Linear Formula: C29H20ClN7O11S3
Product Type: Chemical
| application(s) | diagnostic assay manufacturing hematology histology |
| color | dark blue |
| composition | Dye content, ≥55% |
| form | powder |
| InChI | 1S/C29H20ClN7O11S3/c30-27 |
| InChI key | YKCWQPZFAFZLBI-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | Nc1c(cc(Nc2ccc(Nc3nc(Cl)n |
| solubility | H2O: 10 mg/mL, blue |
| storage temp. | room temp |
| Application: | When immobilized using an insoluble porous support matrix such as agarose, Cibacron Blue 3GA is used for affinity chromatography purification of enzymes. This affinity has been attributed to a structural similarity between the dye and the natural ligands for proteins with cofactor binding domains. |
| Biochem/physiol Actions: | Cibacron Blue 3GA is an anionic anthraquinone dye. It acts as a P2-purinoceptor antagonist and inhibits stimulus-evoked glutamate release by rat brain cortical tissue. Cibacron Blue 3GA inhibits OXA-1 and OXA-2 β-lactamases and was used to observe the binding of ligands to OXA-1 β-lactamase by monitoring tryptophan fluorescence. |
| Packaging: | 1 g in poly bottle |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | room temp |
| UNSPSC | 12171500 |

