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Biotin-maleimide

SIGMA/B1267 - ≥95% (TLC), powder

Synonym: N-Biotinoyl-N′-(6-maleimidohexanoyl)hydrazide

CAS Number: 116919-18-7
Empirical Formula (Hill Notation): C20H29N5O5S
Molecular Weight: 451.54
MDL Number: MFCD28397114
Linear Formula: C20H29N5O5S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-B1267-25MG 25 mg
$155.00
1/EA
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45-B1267-100MG 100 mg
$490.00
1/EA
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assay ≥95% (TLC)
form powder
InChI 1S/C20H29N5O5S/c26-15(7-2-1-5-11-25-17(28)9-10-18(25)29)23-24-16(27)8-4-3-6-14-19-13(12-31-14)21-20(30)22-19/h9-10,13-14,19H,1-8,11-12H2,(H,23,26)(H,24,27)(H2,21,22,30)/t13-,14-,19-/m0/s1
InChI key VAPZWEFPQRDVHR-NJSLBKSFSA-N
Quality Level 200 
SMILES string O=C(CCCCCN1C(=O)C=CC1=O)NNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23
solubility acetic acid: 20 mg/mL
storage temp. 2-8°C
Application: Biotin-maleimide- 0.01 mg/ml in PBS containing 0.1% Tween 20, incubated for 1 h at room temperature can be used to detect deprotected cysteine thiols present on immobilized peptides.
Application: Sulfhydryl-specific biotinylation reagent. Couples by highly efficient thioether linkage. Typically used to couple to intrinsic sulfhydryls, e.g. protein, and avoid modification of primary amine.
Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description: Biotin-maleimide is a biotin specific thiol containing reagent used to biotinylate different proteins through artificially induced or natural sulphadryl group. It can be used as a universal, multipurpose, thiol-specific probe. Biotin-maleimide can also be used in dot blots to detect protein SH groups.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (TLC)
Storage Temp. 2-8°C
UNSPSC 12352203

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