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Bradykinin Fragment 1-5

SIGMA/B1401 - ≥97% (HPLC)

CAS Number: 23815-89-6
Empirical Formula (Hill Notation): C27H40N8O6
Molecular Weight: 572.66
MDL Number: MFCD00076260
Linear Formula: C27H40N8O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B1401-1MG 1 mg
 $83.30
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45-B1401-5MG 5 mg
 $293.00
1/EA		 Add To Favorites

 

assay ≥97% (HPLC)
form powder
InChI 1S/C27H40N8O6/c28-18(9-4-12-31-27(29)30)24(38)35-14-6-11-21(35)25(39)34-13-5-10-20(34)23(37)32-16-22(36)33-19(26(40)41)15-17-7-2-1-3-8-17/h1-3,7-8,18-21H,4-6,9-16,28H2,(H,32,37)(H,33,36)(H,40,41)(H4,29,30,31)
InChI key USSUMSBPLJWFSZ-UHFFFAOYSA-N
Quality Level 200 
SMILES string NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(O)=O
storage temp. −20°C
UniProt accession no. P01042 
Amino Acid Sequence: Arg-Pro-Pro-Gly-Phe
Biochem/physiol Actions: The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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