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BAX Inhibiting Peptide V5

SIGMA/B1436 - ≥97% (HPLC), lyophilized powder

Synonym: BIP-V5

CAS Number: 579492-81-2
Empirical Formula (Hill Notation): C27H50N6O6S
Molecular Weight: 586.79
MDL Number: MFCD04974826
Linear Formula: C27H50N6O6S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B1436-5MG 5 mg
 $194.00
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assay ≥97% (HPLC)
form lyophilized powder
InChI 1S/C27H50N6O6S/c1-16(2)15-20(24(35)31-19(27(38)39)9-6-7-12-28)32-23(34)18(11-14-40-5)30-25(36)21-10-8-13-33(21)26(37)22(29)17(3)4/h16-22H,6-15,28-29H2,1-5H3,(H,30,36)(H,31,35)(H,32,34)(H,38,39)/t18-,19-,20-,21-,22-/m0/s1
InChI key NHMUTADCTDDWPV-YFNVTMOMSA-N
Quality Level 200 
SMILES string S(CC[C@H](NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O)C
storage temp. −20°C
Amino Acid Sequence: Val-Pro-Met-Leu-Lys
Biochem/physiol Actions: BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet and anti-cancer drug.
Biochem/physiol Actions: Bax-mediated apoptosis inhibitor; membrane permeable pentapeptide based on the Ku70-Bax inhibiting domain.
Other Notes: Lyophilized from 0.1% TFA in H2O
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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