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Bradykinin Fragment 1-7

SIGMA/B1651 - ≥97% (HPLC)

Synonym: 1-7-Bradykinin

CAS Number: 23815-87-4
Empirical Formula (Hill Notation): C35H52N10O9
Molecular Weight: 756.85
MDL Number: MFCD00076262
Linear Formula: C35H52N10O9
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-B1651-1MG 1 mg
$95.50
1/EA
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assay ≥97% (HPLC)
color white
form powder
InChI 1S/C35H52N10O9/c36-22(10-4-14-39-35(37)38)31(50)44-16-6-12-26(44)33(52)43-15-5-11-25(43)30(49)40-19-28(47)41-23(18-21-8-2-1-3-9-21)29(48)42-24(20-46)32(51)45-17-7-13-27(45)34(53)54/h1-3,8-9,22-27,46H,4-7,10-20,36H2,(H,40,49)(H,41,47)(H,42,48)(H,53,54)(H4,37,38,39)
InChI key CRROPKNGCGVIOG-UHFFFAOYSA-N
Quality Level 200 
SMILES string NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(CO)C(=O)N4CCCC4C(O)=O
storage temp. −20°C
UniProt accession no. P01161 
Amino Acid Sequence: Arg-Pro-Pro-Gly-Phe-Ser-Pro
Application: Bradykinin Fragment 1-7 has been used as an external calibrant/standard in the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis of protein spots.
Application: Bradykinin Fragment 1-7 is used in research on the specificity and kinetics of kininase(s).
Biochem/physiol Actions: Bradykinin (BK) is a pro-inflammatory mediator and a neuromediator. It modulates several vascular and renal functions. Bradykinin (BK) plays a key role in inducing vascular permeability and mitogenesis. It helps to activate the liberation of nitric oxide in inflammatory and cancer tissues.
General description: Bradykinin fragment 1-7 (BK-(1-7)), an endogenous peptide, is present in plasma.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (HPLC)
Storage Temp. −20°C
UNSPSC 12352209

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