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Bisoprolol hemifumarate salt

SIGMA/B2185 - ≥98% (HPLC), solid

Synonym: 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemifumarate salt

CAS Number: 104344-23-2
Empirical Formula (Hill Notation): C18H31NO4 · .5C4H4O4
Molecular Weight: 383.48
MDL Number: MFCD00792743
Linear Formula: C18H31NO4 · .5C4H4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B2185-10MG 10 mg
 $171.00
1/EA		 Add To Favorites
45-B2185-50MG 50 mg
 $683.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white
form solid
InChI 1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+
InChI key VMDFASMUILANOL-WXXKFALUSA-N
originator Teva
Quality Level 100 
SMILES string OC(=O)C=CC(O)=O.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc2ccc(COCCOC(C)C)cc2
solubility DMSO: >20 mg/mL
Application: Bisoprolol hemifumarate salt has been used as a β-adrenergic receptor (β-AR) antagonist in cardiac fibrosis mice model.
Biochem/physiol Actions: Bisoprolol hemifumarate is useful in oral formulations due to its high bioavailability. It also shows long elimination half-life.
Biochem/physiol Actions: Cardioselective β1-adrenoceptor antagonist.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound was developed by Teva . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 10, 50 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P264 - P270 - P301 + P312 + P330 - P501
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
UNSPSC 12352200

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