BEPP monohydrochloride
SIGMA/B2938 - ≥98% (HPLC)
Synonym: 1H-
CAS Number: 455311-98-5
Empirical Formula (Hill Notation): C23H23N3O2 HCl
Molecular Weight: 409.91
MDL Number: MFCD00964481
Linear Formula: C23H23N3O2 HCl
Product Type: Chemical
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B2938-25MG.
| assay | ≥98% (HPLC) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C23H23N3O2.ClH/c24-23- |
| InChI key | KDMXJFUGIDGZQL-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Cl.OC(COc1ccccc1)CN2C(=N) |
| solubility | DMSO: >10 mg/mL |
| storage condition | desiccated |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | BEPP is a double-strand RNA-dependent protein kinase (PKR) activator. |
| Biochem/physiol Actions: | BEPP is a double-strand RNA-dependent protein kinase (PKR) activator. The double-strand RNA (dsRNA)-dependent protein kinase is a ubiquitously expressed serine threonine kinase, inducible by interferon γ. PRK is involved in several curtail cellular regulations including phosphorylation of eIF2α (which leads to inhibition of protein synthesis and eliciting antivirus and antitumor activities), modulating activities of eIF2α, NF-κB, ATF-3, and p53. BEPP also inhibits the growth of a human lung cancer cell line overexpressing PKR. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |