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BEPP monohydrochloride

SIGMA/B2938 - ≥98% (HPLC)

Synonym: 1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride

CAS Number: 455311-98-5
Empirical Formula (Hill Notation): C23H23N3O2 HCl
Molecular Weight: 409.91
MDL Number: MFCD00964481
Linear Formula: C23H23N3O2 HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B2938-5MG 5 mg
 $188.00
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45-B2938-25MG 25 mg
 $580.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to off-white
form powder
InChI 1S/C23H23N3O2.ClH/c24-23-25(15-18-9-3-1-4-10-18)21-13-7-8-14-22(21)26(23)16-19(27)17-28-20-11-5-2-6-12-20;/h1-14,19,24,27H,15-17H2;1H
InChI key KDMXJFUGIDGZQL-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl.OC(COc1ccccc1)CN2C(=N)N(Cc3ccccc3)c4ccccc24
solubility DMSO: >10 mg/mL
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: BEPP is a double-strand RNA-dependent protein kinase (PKR) activator.
Biochem/physiol Actions: BEPP is a double-strand RNA-dependent protein kinase (PKR) activator. The double-strand RNA (dsRNA)-dependent protein kinase is a ubiquitously expressed serine threonine kinase, inducible by interferon γ. PRK is involved in several curtail cellular regulations including phosphorylation of eIF2α (which leads to inhibition of protein synthesis and eliciting antivirus and antitumor activities), modulating activities of eIF2α, NF-κB, ATF-3, and p53. BEPP also inhibits the growth of a human lung cancer cell line overexpressing PKR.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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