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Berberine chloride form

SIGMA/B3251

Synonym: Benzodioxide; Berberine HCl; Natural Yellow 18

CAS Number: 633-65-8
Empirical Formula (Hill Notation): C20H18ClNO4
Molecular Weight: 371.81
EC Number: 211-195-9
MDL Number: MFCD00011939
Linear Formula: C20H18ClNO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B3251-5G 5 g
 $63.70
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45-B3251-10G 10 g
 $122.00
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45-B3251-25G 25 g
 $255.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B3251-5G.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B3251-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B3251-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B3251-5G

 

form powder
InChI 1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
InChI key VKJGBAJNNALVAV-UHFFFAOYSA-M
Quality Level 200 
SMILES string COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
solubility methanol: soluble
Application: Berberine Chloride is a fluorescent stain used to stain heparin in mast cells. Berberine upregulates the expression of Pgp in hepatoma cells.
Application: Fluorescent stain for heparin in mast cells
Biochem/physiol Actions: An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
General description: Berberine Chloride form or Natural Yellow 18, is also known as 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo (5,6-a) quinolizinium is a benzyl tetra isoquinoline plant alkaloid. Berberine contains a quaternary base and is commercially available in berberine chloride form.
Packaging: 5, 10, 25 g in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Colour Index Number 75160
UNSPSC 12171500

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