Bradykinin acetate salt

SIGMA/B3259 - powder, ≥98% (HPLC)

CAS Number: 6846-03-3
Empirical Formula (Hill Notation): C₅₀H₇₃N₁₅O₁₁ · xC₂H₄O₂
Molecular Weight: 1060.21 (free base basis)
EC Number: 227-781-2
MDL Number: MFCD00076258
Linear Formula: C₅₀H₇₃N₁₅O₁₁ · xC₂H₄O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-B3259-1MG	1 mg	$33.10 1/EA		Add To Favorites
45-B3259-5MG	5 mg	$82.80 1/EA		Add To Favorites
45-B3259-10MG	10 mg	$125.00 1/EA		Add To Favorites
45-B3259-25MG	25 mg	$253.00 1/EA		Add To Favorites
45-B3259-100MG	100 mg	$837.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white
form	powder
InChI	1S/C50H73N15O11/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55/h1-6,12-15,32-39,66H,7-11,16-29,51H2,(H,58,70)(H,59,67)(H,60,69)(H,61,71)(H,62,68)(H,75,76)(H4,52,53,56)(H4,54,55,57)/t32-,33-,34-,35-,36-,37-,38-,39-/m0/s1
InChI key	QXZGBUJJYSLZLT-FDISYFBBSA-N
Quality Level	100
SMILES string	N2([C@@H](CCC2)C(=O)NCC(=O)N[C@@H](Cc5ccccc5)C(=O)N[C@@H](CO)C(=O)N3[C@@H](CCC3)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)C(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCN=C(N)N
solubility	0.1 M acetic acid: 25 mg/mL, clear, colorless
storage condition	desiccated
storage temp.	−20°C
UniProt accession no.	P01042

Amino Acid Sequence:	Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
Application:	Bradykinin acetate salt has been used: • to stimulate the contraction of guinea pig ileum • as a contractile agent in fibroblasts • In the stimulation of endothelium of human subcutaneous artery • To evoke Ca²⁺ signals in neuroblastoma-glioma hybrid cell line, NG108-15
Biochem/physiol Actions:	Activates pain receptors; induces smooth muscle contraction; activates Ca²⁺-dependent nitric oxide synthetase; increases capillary permeability.
Biochem/physiol Actions:	Bradykinin is a pro-inflammatory peptide that acts through G-protein-coupled receptors. It activates sphingolipid metabolism. Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content. The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids. Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability. The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352106

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.