Berberine hemisulfate salt
SIGMA/B3412 - ≥95%
Synonym: Natural Yellow 18
CAS Number: 633-66-9
Empirical Formula (Hill Notation): C20H18NO4 · 0.5O4S
Molecular Weight: 384.39
MDL Number: MFCD00031743
Linear Formula: C20H18NO4 · 1/2SO4
Product Type: Chemical
| assay | ≥95% |
| form | powder |
| InChI | 1S/2C20H18NO4.H2O4S/c2*1- |
| InChI key | OJVABJMSSDUECT-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | [O-]S([O-])(=O)=O.COc1ccc |
| solubility | methanol: soluble |
| Application: | Fluorescent stain for heparin in mast cells |
| Biochem/physiol Actions: | An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs. |
| Packaging: | 10 g in glass bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264 - P270 - P301 + P312 + P330 - P501 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | ≥95% |
| Colour Index Number | 75160 |
| UNSPSC | 12171500 |


