Bovine Pulmonary Artery Smooth Muscle Cells: BPASMC (Cryovial)
SIGMA/B352-05
Product Type: Product-on-demand
Cell Applications : Bovine Pulmonary Artery Smooth Muscle Cells, BPASMC (left). BPASMC immunolabeled for smooth muscle-specific alpha-actin (ABC method, right).
| biological source | bovine pulmonary artery (tunica intima and media) |
| growth mode | Adherent |
| karyotype | 2n = 60 |
| manufacturer/tradename | Cell Applications, Inc |
| morphology | smooth muscle |
| packaging | pkg of 500,000 cells |
| relevant disease(s) | cardiovascular diseases |
| shipped in | dry ice |
| storage temp. | −196°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | cell growth, signaling, receptor transactivation and suppression, vascular remodeling |
| Biochem/physiol Actions: | Artery |
| General description: | Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details. BPASMC have been used in studies relevant to pulmonary hypertension characterized by hyperproliferation of pulmonary artery smooth muscle cells, the process shown to be mediated by hypoxia-induced expression of Bcl-xl (Suzuki, 2007). Additionally, they were used to elucidate the PKC-α dependent mechanisms of proMMP-2 activation and other signaling events in smooth muscle cells under pro-inflammatory conditions related to cell growth (Chakraborti, 2009; Roy, 2011, 2013; Dey, 2012; Chowdhury, 2013; Shaikh, 2013). Characterization: positive for smooth muscle cell specific alpha-actin expression. |
| Other Notes: | Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO |
| Preparation Note: | • 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO • Can be cultured at least 16 doublings |
| Preparation Note: | Please refer to the BPASMC Culture Protocol  . |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −196°C |
| UNSPSC | 41106514 |