Bacitracin zinc salt

SIGMA/B5150 - from Bacillus licheniformis, ~70,000 U/g

Synonym: Zinc bacitracin

CAS Number: 1405-89-6
Empirical Formula (Hill Notation): C₆₆H₁₀₁N₁₇O₁₆SZn
Molecular Weight: 1486.07
EC Number: 215-787-8
MDL Number: MFCD00130598
Linear Formula: C₆₆H₁₀₁N₁₇O₁₆SZn
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-B5150-250KU	250000 units	$88.10 1/EA		Add To Favorites
45-B5150-1250KU	1250000 units	$301.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-positive bacteria
biological source	Bacillus licheniformis
form	powder
InChI	1S/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-72-32-48(100-66)63(97)80-43(26-34(4)5)59(93)75-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)76-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-73-39)77-60(94)44(27-38-18-13-12-14-19-38)81-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)74-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,73)(H,71,89)(H,74,90)(H,75,93)(H,76,98)(H,77,94)(H,78,96)(H,79,95)(H,80,97)(H,81,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-;/m0./s1
InChI key	NKULICGUDKGGRL-FCHFGNCGSA-L
mode of action	cell wall synthesis \| interferes
mp	250 °C (dec.) (lit.)
Quality Level	200
SMILES string	[Zn++].CCC(C)C(N)C1=NCC(S1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC([O-])=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC
specific activity	~70,000 U/g
storage temp.	2-8°C

Application:	Bacitracin zinc salt is a peptide antibiotic used to study dysruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. It is used to study the biosynthesis of sterols and squalene.
Biochem/physiol Actions:	Bacitracin is a protease inhibitor. Antimicrobial spectrum: Gram-positive bacteria. Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.
General description:	Chemical structure: peptide
Other Notes:	Keep container tightly closed in a dry and well-ventilated place.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

activity	specific activity: ~70,000 U/g
mp	250 °C (dec.) (lit.)
Storage Temp.	2-8°C
UNSPSC	51282002

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