des-Arg⁹-[Leu⁸]-Bradykinin acetate salt

SIGMA/B6769 - ≥97% (HPLC)

Synonym: Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu

CAS Number: 115035-45-5
Empirical Formula (Hill Notation): C₄₁H₆₃N₁₁O₁₀
Molecular Weight: 870.01
MDL Number: MFCD00133250
Linear Formula: C₄₁H₆₃N₁₁O₁₀
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-B6769-25MG	25 mg	$442.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
color	white
form	powder
InChI	1S/C41H63N11O10.C2H4O2/c1-24(2)20-28(40(61)62)48-36(57)31-14-8-17-50(31)38(59)29(23-53)49-34(55)27(21-25-10-4-3-5-11-25)47-33(54)22-46-35(56)30-13-7-18-51(30)39(60)32-15-9-19-52(32)37(58)26(42)12-6-16-45-41(43)44;1-2(3)4/h3-5,10-11,24,26-32,53H,6-9,12-23,42H2,1-2H3,(H,46,56)(H,47,54)(H,48,57)(H,49,55)(H,61,62)(H4,43,44,45);1H3,(H,3,4)/t26-,27-,28-,29-,30-,31-,32-;/m0./s1
InChI key	XBFMNOKHQZCARQ-XXZMQFNDSA-N
Quality Level	200
SMILES string	CC(O)=O.CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@@H](N)CCCNC(N)=N)C(O)=O
storage temp.	−20°C

Amino Acid Sequence:	Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu
Application:	The Bradkykinin amid peptide des-Arg9-[Leu8]-Bradykinin is used as a bradykinin-1 receptor (B1R) antagonist frequently in comparison with the B1 receptor agonist des-Arg9-bradykinin.
Biochem/physiol Actions:	Bradykinin receptor antagonist.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352209

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