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BRD7389

SIGMA/B7563 - ≥98% (HPLC)

Synonym: 1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione; 1-[(2-Phenylethyl)amino]-naphtho-3H-[1,2,3-de]quinoline-2,7-dione

CAS Number: 376382-11-5
Empirical Formula (Hill Notation): C24H18N2O2
Molecular Weight: 366.41
MDL Number: MFCD02924820
Linear Formula: C24H18N2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B7563-5MG 5 mg
 $187.86
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assay ≥98% (HPLC)
color orange
form powder
InChI 1S/C24H18N2O2/c27-23-17-10-5-4-9-16(17)21-20-18(23)11-6-12-19(20)26-24(28)22(21)25-14-13-15-7-2-1-3-8-15/h1-12,25H,13-14H2,(H,26,28)
InChI key XASCINRGTHLHGM-UHFFFAOYSA-N
Quality Level 100 
SMILES string [nH]1c2c3c(c5c([c](c3ccc2)=O)cccc5)c([c]1=O)NCCc4ccccc4
solubility DMSO: >20 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: BRD7389 is an inhibitor of the RSK kinase family.
Biochem/physiol Actions: BRD7398 is a RSK kinase inhibitor that induces insulin expression and differentiation of pancreatic alpha into beta cells. BRD7398 inhibits RSK1, RSK2 and RSK3; IC50 values of 1.5, 2.4 and 1.2 uM, respectively. Treatment of mouse aTC1 cells with BRD7398 induced expression of b-cell markers Pdx1, Pax4, Iapp and Npy and also induced insulin production.
Features and Benefits: This compound is featured on the MAPKAPs  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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