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4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one

SIGMA/B8279 - solid

Synonym: Ro 20-1724

CAS Number: 29925-17-5
Empirical Formula (Hill Notation): C15H22N2O3
Molecular Weight: 278.35
MDL Number: MFCD00077397
Linear Formula: C15H22N2O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B8279-100MG 100 mg
 $122.00
1/EA		 Add To Favorites
45-B8279-500MG 500 mg
 $564.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B8279-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B8279-500MG

 

assay ≥98% (HPLC)
biological source synthetic (organic)
form solid
InChI 1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)
InChI key PDMUULPVBYQBBK-UHFFFAOYSA-N
Quality Level 200 
SMILES string CCCCOc1cc(CC2CNC(=O)N2)ccc1OC
solubility ethanol: 7 mg/mL
  H2O: insoluble
storage temp. room temp
Application: 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one has been used:
• as a cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitor to treat cells for the determination of intracellular cAMP levels
• as a component of serum-free medium
• as phosphodiesterase inhibitor in order to study the effects of protease-activated receptor-1 (PAR-1) activation on cAMP levels
Biochem/physiol Actions: Inhibitor of cAMP phosphodiesterase. IC50 33 μM in vascular smooth muscle of the aorta.
Features and Benefits: This compound is a featured product for Cyclic Nucleotide research. Click here  to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Phosphodiesterases  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 100, 500 mg in poly bottle
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 41106305

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