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Bambuterol hydrochloride

SIGMA/B8684 - >98% (HPLC), powder

Synonym: Dimethylcarbmic acid 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester

CAS Number: 81732-46-9
Empirical Formula (Hill Notation): C18H30N3O5Cl
Molecular Weight: 403.90
MDL Number: MFCD03427293
Linear Formula: C18H29N3O5 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B8684-10MG 10 mg
 $135.00
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45-B8684-50MG 50 mg
 $501.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B8684-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B8684-50MG

 

assay >98% (HPLC)
color off-white
form powder
InChI 1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7;/h8-10,15,19,22H,11H2,1-7H3;1H
InChI key LBARATORRVNNQM-UHFFFAOYSA-N
originator AstraZeneca
Quality Level 100 
SMILES string Cl.CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C
solubility H2O: soluble ~33 mg/mL
storage condition desiccated
Application: Bambuterol hydrochloride has been used as a β2-adrenergic receptor (β2-AR) agonist to study its effects on graft versus host disease (GVHD) while preserving the graft-versus-tumor (GvT) effect. It has also been used in the preparation of bambuterol-poly vinyl chloride (Bb-PVC) membrane sensors for the determination of bambuterol in the pharmaceutical dosage form.
Biochem/physiol Actions: β-adrenoceptor agonist; bronchodilator; anti-asthmatic; terbutaline prodrug
Biochem/physiol Actions: Bambuterol hydrochloride is used for prophylaxis and also to treat chronic bronchitis and chronic asthma in pediatrics.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound was developed by AstraZeneca . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Bambuterol is present in various tissues, like , intestine, lungs, liver and heart. It is also found in serum.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >98% (HPLC)
UNSPSC 12352200

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