Advanced Search



Betulinic acid

SIGMA/B8936 - ≥98% (HPLC)

Synonym: 3β-Hydroxy-20(29)-lupaene-28-oic acid; Lupatic acid; Mairin

CAS Number: 472-15-1
Empirical Formula (Hill Notation): C30H48O3
Molecular Weight: 456.70
EC Number: 207-448-8
MDL Number: MFCD00009619
Linear Formula: C30H48O3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-B8936-5MG 5 mg
$0.00
1/EA
CALL FOR PRICE
Add To Favorites
45-B8936-25MG 25 mg
$212.00
1/EA
Add To Favorites

 

application(s) metabolomics
vitamins, nutraceuticals, and natural products
assay ≥98% (HPLC)
form powder
InChI 1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
InChI key QGJZLNKBHJESQX-FZFNOLFKSA-N
mp 295-298 °C (dec.) (lit.)
Quality Level 100 
SMILES string CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
storage temp. 2-8°C
Application: Betulinic acid (BetA) has been used:
• to test its effects as an antiviral agent against Dengue virus (DENV)
• as a sterol regulatory element-binding protein (SREBP) inhibitor to repress the lipid metabolism and proliferation of clear cell renal cell carcinoma (ccRCC) cells
• as a treatment to test its anti-tumor properties for cell viability and apoptotic cell death assays in multiple myeloma models

Biochem/physiol Actions: Betulinic acid displays many biological and pharmacological properties such as anticancer, anti-inflammatory, anti-bacterial, anti-human immunodeficiency virus (HIV), and anti-malarial properties.
Biochem/physiol Actions: Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism.
General description: Betulinic acid (BetA) is a natural product mostly sourced from the birch tree (Betula spp.). This pentacyclic lupanetype triterpenoid is also associated with other species such as Syzygium spp., Diospyros spp., Ziziphus spp., and Paeonia spp..
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
mp 295-298 °C (dec.) (lit.)
Storage Temp. 2-8°C
UNSPSC 12352205

The following items have been added to your cart:

Choose a favorite list for this item:

Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Tariffs & Effects on Pricing

Tariff note: As we navigate the current environment of tariff surcharges and mid-year manufacturer price increases, we want to keep you informed. While we have avoided making specific decisions thus far, we anticipate that we will be forced to implement a cost adjustment policy to offset the fees we have already been absorbing. We are committed to transparency and moderation in this process.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top