(−)-Bilobalide from Ginkgo biloba leaves

SIGMA/B9031 - ≥93% (HPLC)

Synonym: Bilobalide

CAS Number: 33570-04-6
Empirical Formula (Hill Notation): C₁₅H₁₈O₈
Molecular Weight: 326.30
MDL Number: MFCD00238547
Linear Formula: C₁₅H₁₈O₈
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-B9031-25MG	25 mg	$498.00 1/EA	Add To Favorites
45-B9031-100MG	100 mg	$1520.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B9031-10MG.

Properties
Descriptions
Safety Info.
Basic Data

assay	≥93% (HPLC)
biological source	plant leaves (Ginkgo biloba)
color	white
form	powder
InChI	1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13-,14+,15+/m0/s1
InChI key	MOLPUWBMSBJXER-YDGSQGCISA-N
Quality Level	100
SMILES string	CC(C)(C)[C@]1(O)CC2OC(=O)C[C@@]23C(=O)OC4OC(=O)[C@H](O)[C@]134
storage temp.	−20°C
technique(s)	HPLC: suitable

Application:	(-)-Bilobalide from Ginkgo biloba leaves has been used as a reference substance to study the antimicrobial activity of different fractions of G.biloba leaves against a number of Gram-positive and negative bacteria and yeasts.
Biochem/physiol Actions:	Bilobalide is an inducer of cytochrome P450 enzymes CYP3A1 and CYP1A2. It exhibits neuroprotective, anti-inflammatory, anti-oxidative and anti-apoptotic properties. Bilobalide, a γ-aminobutyric acid (GABA) A_A-rho, 5-hydroxytryptamine type 3 (5-HT(3)) receptor antagonist, may be used to study the function of these receptors in the brain processes such as cognition and memory. It serves as a specific platelet-activating factor receptor antagonist, which helps in the treatment of cardiovascular (Alzheimer′s disease) and cerebrovascular diseases.
Biochem/physiol Actions:	Bioactive terpenoid found in Ginkgo biloba.
General description:	Bilobalide is a biologically active terpenic trilactone (terpenoid) extracted from Ginkgo biloba. It is synthesized from geranylgeranyl pyrophosphate (GGPP).
Packaging:	10 mg in glass insert
Packaging:	25, 100 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥93% (HPLC)
Storage Temp.	−20°C
UNSPSC	85151701

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