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(−)-Bilobalide from Ginkgo biloba leaves

SIGMA/B9031 - ≥93% (HPLC)

Synonym: Bilobalide

CAS Number: 33570-04-6
Empirical Formula (Hill Notation): C15H18O8
Molecular Weight: 326.30
MDL Number: MFCD00238547
Linear Formula: C15H18O8
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B9031-10MG 10 mg
 $0.00
1/EA
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45-B9031-25MG 25 mg
 $0.00
1/EA
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45-B9031-100MG 100 mg
 $1420.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B9031-10MG.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: B9031-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: B9031-25MG

 

assay ≥93% (HPLC)
biological source plant leaves (Ginkgo biloba)
color white
form powder
InChI 1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13-,14+,15+/m0/s1
InChI key MOLPUWBMSBJXER-YDGSQGCISA-N
Quality Level 100 
SMILES string CC(C)(C)[C@]1(O)CC2OC(=O)C[C@@]23C(=O)OC4OC(=O)[C@H](O)[C@]134
storage temp. −20°C
technique(s) HPLC: suitable
Application: (-)-Bilobalide from Ginkgo biloba leaves has been used as a reference substance to study the antimicrobial activity of different fractions of G.biloba leaves against a number of Gram-positive and negative bacteria and yeasts.
Biochem/physiol Actions: Bilobalide is an inducer of cytochrome P450 enzymes CYP3A1 and CYP1A2. It exhibits neuroprotective, anti-inflammatory, anti-oxidative and anti-apoptotic properties. Bilobalide, a γ-aminobutyric acid (GABA) AA-rho, 5-hydroxytryptamine type 3 (5-HT(3)) receptor antagonist, may be used to study the function of these receptors in the brain processes such as cognition and memory. It serves as a specific platelet-activating factor receptor antagonist, which helps in the treatment of cardiovascular (Alzheimer′s disease) and cerebrovascular diseases.
Biochem/physiol Actions: Bioactive terpenoid found in Ginkgo biloba.
General description: Bilobalide is a biologically active terpenic trilactone (terpenoid) extracted from Ginkgo biloba. It is synthesized from geranylgeranyl pyrophosphate (GGPP).
Packaging: 10 mg in glass insert
Packaging: 25, 100 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥93% (HPLC)
Storage Temp. −20°C
UNSPSC 85151701

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