5-Bromo-2′-deoxyuridine

SIGMA/B9285 - BioUltra, ≥99%

Synonym: 5-BrdU; 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil; 5-Bromouracil deoxyriboside; BUdR

CAS Number: 59-14-3
Empirical Formula (Hill Notation): C₉H₁₁BrN₂O₅
Molecular Weight: 307.10
EC Number: 200-415-9
MDL Number: MFCD00006529
Linear Formula: C₉H₁₁BrN₂O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-B9285-50MG	50 mg	$67.00 1/EA	Add To Favorites
45-B9285-250MG	250 mg	$122.00 1/EA	Add To Favorites
45-B9285-1G	1 g	$319.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B9285-1G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99%
biological source	synthetic (organic)
cation traces	Al: ≤0.0005%
	Ca: ≤0.01%
	Cu: ≤0.0005%
	Fe: ≤0.0005%
	K: ≤0.005%
	Mg: ≤0.0005%
	Na: ≤0.05%
	NH₄⁺: ≤0.05%
	Pb: ≤0.001%
	Zn: ≤0.0005%
form	powder
ign. residue	≤0.1%
impurities	≤0.005% Phosphorus (P)
	≤0.1% Insoluble matter
InChI	1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI key	WOVKYSAHUYNSMH-RRKCRQDMSA-N
mp	191-194 °C (dec.) (lit.)
product line	BioUltra
Quality Level	200
SMILES string	OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(Br)C(=O)NC2=O
solubility	NH₄OH: 0.1 M at 20 °C, clear, colorless
storage temp.	−20°C

Application:	5-Bromo-2′-deoxyuridine has been used: • to label proliferating cells in pregnant mice in cell proliferation assay • to study the time course of cell proliferation at various times following ischemia, to confirm re-entry of MKI67+ cells in cell cycle to germ cells • in 5′-Bromo-2′Deoxyuridine (BrdUrd) staining of fibroblasts
Biochem/physiol Actions:	5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Biochem/physiol Actions:	5′-Bromo-2-deoxyuridine (BrdU) staining is predominantly used to observe the multiplication of tumor cells and other tissues in vivo.
Biochem/physiol Actions:	Thymidine analog used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase.
General description:	5′-Bromo-2-deoxyuridine (BrdU) is a carcinogen that may be absorbed by skin or inhalation. BrdU solutions are sensitive to light.
Other Notes:	2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
Packaging:	1 g in poly bottle
Packaging:	50, 250 mg in poly bottle

Symbol	GHS08
Signal word	Danger
Hazard statements	H340 - H361fd
Precautionary statements	P201 - P202 - P280 - P308 + P313 - P405 - P501
Hazard Codes	T
Risk Statements	46-61
Safety Statements	53-45
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2

Purity	≥99%
mp	191-194 °C (dec.) (lit.)
Storage Temp.	−20°C
UNSPSC	41106305

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