BTA-1
SIGMA/B9934 - ≥98% (HPLC), solid
Synonym: 2-
CAS Number: 439858-28-3
Empirical Formula (Hill Notation): C14H12N2S
Molecular Weight: 240.32
MDL Number: MFCD04974146
Linear Formula: C14H12N2S
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | yellow |
| form | solid |
| InChI | 1S/C14H12N2S/c1-15-11-8-6 |
| InChI key | FHJRKGXJBXPBGA-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | CNc1ccc(cc1)-c2nc3ccccc3s |
| solubility | DMSO: soluble ~10 mg/mL |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | BTA-1 is a fluorescent thioflavin-T derivative with 50-fold higher affinity for β-amyloid aggregates. |
| Biochem/physiol Actions: | BTA-1 is a probe for β-amyloid aggregates; fluorescent thioflavin-T derivative; exhibits high affinity for amyloid deposits; displays 50-fold higher affinity than thioflavin-T; selectively stains cerebral plaques and cerebrovascular amyloid deposits in the brains of PS1/APP transgenic mice, as well as Aβ fibrils in postmortem brain tissue obtained from AD patients; crosses the blood brain barrier. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |

