Chloroperoxidase from Caldariomyces fumago
SIGMA/C0278 - buffered aqueous suspension, ≥3,000 units/mL
Synonym: Chloride Peroxidase; Chloride:hydrogen-
CAS Number: 9055-20-3
MDL Number: MFCD00130774
Product Type: Chemical
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| concentration | ≥3,000 units/mL |
| form | buffered aqueous suspension |
| mol wt | 42 kDa |
| Quality Level | 200  |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| Application: | A useful alternative to lactoperoxidase for 131I ion labeling studies, for bromination of proteins, and for 36Cl labeling of macromolecules in long-term isolation procedures. |
| Application: | Chloroperoxidase from Caldariomyces fumagois is useful alternative to lactoperoxidase for 131I ion labeling studies, for bromination of proteins, and for 36Cl labeling of macromolecules in long-term isolation procedures. It has been used to study biocatalytic oxidation in polymersome nanoreactors . |
| Application: | It has been used to study biocatalytic oxidation in polymersome nanoreactors. |
| Biochem/physiol Actions: | Chloroperoxidase (CPO) is secreted from fungus and exhibits a broad spectrum of chemical reactivities. It is a peroxide-dependent chlorinating enzyme and it also catalyzes peroxidase, catalase and cytochrome P450-type reactions of dehydrogenation, hydrogenperoxide (H2O2) decomposition and oxygen insertion, respectively. The enzyme has magnetic and spectroscopic properties similar to that of cyctochrome P-450. CPO from the fungus Caldariomyces fumago has the capacity to chlorinate aromatic hydrocarbons, including polycyclic aromatic hydrocarbons (PAHs). PAHs are considered to be a potential health risk because of their possible carcinogenic and mutagenic activities and are widely dispersed in the environment. |
| General description: | Chloroperoxidase is a heme containing glycoprotein that is secreted from fungus. Chloroperoxidase (CPO) is a extracellular heme glycoenzyme containing ferriprotoporphyrin IX as the prosthetic group. |
| Other Notes: | One unit will catalyze the conversion of 1.0 μmole of monochlorodimedon to dichlorodimedon per min at pH 2.75 at 25 °C in the presence of potassium chloride and H2O2. |
| Packaging: | 12500 units in poly bottle |
| Physical form: | Crude suspension in 0.1 M sodium phosphate, pH ~4.5 |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H334 |
| Precautionary statements | P261 - P284 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| Enzyme Commission (EC) Number | 1.11.1.10 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |