Cholesteryl linoleate
SIGMA/C0289 - ≥98% (HPLC; detection at 205 nm)
Synonym: 3β-Hydroxy-5-cholestene 3-linoleate; 5-Cholesten-3β-ol 3-linoleate; Cholesteryl 9,12-
CAS Number: 604-33-1
Empirical Formula (Hill Notation): C45H76O2
Molecular Weight: 649.08
EC Number: 210-065-9
MDL Number: MFCD00003644
Linear Formula: C45H76O2
Product Type: Chemical
Representative of vacuum-sealed clear ampule packaging. Non-uniform tips are an inherent feature in this sealing process.
| assay | ≥98% (HPLC; detection at 205 nm) |
| biological source | synthetic (organic) |
| form | powder |
| functional group | ester |
| InChI | 1S/C45H76O2/c1-7-8-9-10-1 |
| InChI key | NAACPBBQTFFYQB-LJAITQKLSA |
| Quality Level | 200  |
| shipped in | ambient |
| SMILES string | CCCCCC=C/CC=C/CCCCCCCC( |
| storage temp. | −20°C |
| Application: | Cholesteryl linoleate was cosonicated with cholesterol to prepare dispersions were prepared to study the cholesterol to phospholipid ratio in red blood cell membrane. It was used as HPLC standard in the analysis of rat liver lipoproteins. |
| Biochem/physiol Actions: | Cholesteryl linoleate is a major cholesterol ester found associated with the neutral core of low density lipoprotein. Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters. The enzyme acid cholesteryl ester hydrolase is responsible for the hydrolysis of cholesteryl esters; a defective enzyme can result in the formation of atherosclerotic lesions in humans. |
| Biochem/physiol Actions: | The most abundant cholesteryl ester in low density lipoprotein (LDL). |
| Packaging: | 1 g in ampule |
| Packaging: | 100, 250 mg in ampule |
| Packaging: | Sealed ampule |
| Preparation Note: | Cholesteryl linoleate yields clear, colorless solution in chloroform at 100 mg/ml. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC; detection at 205 nm) |
| Storage Temp. | −20°C |
| UNSPSC | 12352211 |