DMT-dC(ac) Phosphoramidite

SIGMA/C113000 - ≥99.0% (reversed phase HPLC)

Synonym: DMT-dC(ac) Amidite; N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N4-Acetyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]

CAS Number: 154110-40-4
Empirical Formula (Hill Notation): C₄₁H₅₀N₅O₈P
Molecular Weight: 771.84
MDL Number: MFCD09842112
Linear Formula: C₄₁H₅₀N₅O₈P
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-C113000-6X5G	5 g	$575.00 6/EA	Add To Favorites
45-C113000-6X10G	10 g	$1010.00 6/EA	Add To Favorites
45-C113000-6X20G	20 g	$1880.00 6/EA	Add To Favorites
45-C113000-100G	100 g	$1480.00 1/EA	Add To Favorites
45-C113000-500G	500 g	$13600.00 1/EA	Add To Favorites
45-C113000-1KG	1 kg	$21070.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

λ	conforms (UV/VIS Identity)
assay	≥98% (³¹P-NMR)
	≥99.0% (reversed phase HPLC)
biological source	non-animal source (no BSE/TSE risk)
color	white to off-white
form	powder
InChI	1S/C41H50N5O8P/c1-28(2)46(29(3)4)55(52-25-11-23-42)54-36-26-39(45-24-22-38(43-30(5)47)44-40(45)48)53-37(36)27-51-41(31-12-9-8-10-13-31,32-14-18-34(49-6)19-15-32)33-16-20-35(50-7)21-17-33/h8-10,12-22,24,28-29,36-37,39H,11,25-27H2,1-7H3,(H,43,44,47,48)/t36-,37+,39+,55?/m0/s1
InChI key	MECWEBCHRKVTNV-RLWDVSNXSA-N
mol wt	771.85 g/mol
nucleoside profile	base: deoxycytidine base protecting group: acetyl 2' protecting group: none 5' protecting group: DMT deprotection: fast/standard
packaging	pkg of 6 × 10 g C113000-6x10G (16 oz Bottle)
product line	Proligo Reagents
Quality Level	200
SMILES string	COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(C)=O)=NC3=O)(c4ccccc4)c5ccc(OC)cc5
solubility	water: insoluble
storage temp.	-10 to -25°C
technique(s)	oligo synthesis: suitable
type	for DNA synthesis

Features and Benefits:

Key Features of dC(ac):

• Ultrafast deprotection: 10 minutes at 65°C with AMA reagent
• Key component in oligonucleotide synthesis
• Industry standard for fast deprotection chemistry
• Operating for AMA deprotection methods without changes
• Consistent lot-to-lot high purity and performance
• Manufactured under a certified ISO 9001 quality system

General description:

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. DMT-dC(ac) Phosphoramidite is an acetyl-protected DNA phosphoramidite used in fast deprotection chemistry for the rapid and high-yield synthesis of high-purity oligonucleotides. The product belongs to MerMade synthesizers.

RIDADR

NONH for all modes of transport

Purity	≥98% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
Storage Temp.	-10 to -25°C
UNSPSC	12352200

To Order From a Quote