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Chlormethiazole hydrochloride

SIGMA/C1240 - ≥98% (HPLC), powder

Synonym: 4-methyl-5-(β-chloroethyl)thiazole hydrochloride; 5-(2-Chloroethyl)-4-methylthiazole hydrochloride; Clomethiazole hydrochloride; Somnevrin hydrochloride

CAS Number: 6001-74-7
Empirical Formula (Hill Notation): C6H8ClNS · HCl
Molecular Weight: 198.11
MDL Number: MFCD00673948
Linear Formula: C6H8ClNS · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C1240-10MG 10 mg
 $147.00
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45-C1240-50MG 50 mg
 $523.00
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assay ≥98% (HPLC)
color off-white
description Store desiccated
form powder
InChI 1S/C6H8ClNS.ClH/c1-5-6(2-3-7)9-4-8-5;/h4H,2-3H2,1H3;1H
InChI key OFXYKSLKNMTBHK-UHFFFAOYSA-N
originator AstraZeneca
Quality Level 100 
SMILES string Cl.Cc1ncsc1CCCl
solubility H2O: soluble >10 mg/mL
Biochem/physiol Actions: Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus. Long term administration of chlormethiazole leads to addiction to the drug.
Biochem/physiol Actions: GABAA agonist; glycine receptor modulator.
Features and Benefits: This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox  and Neuroscience  products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound was developed by AstraZeneca . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 10, 50 mg in glass bottle
Purity ≥98% (HPLC)
UNSPSC 12352200

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