Sodium cholate hydrate

SIGMA/C1254 - from bovine and/or ovine bile, ≥99%

Synonym: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt; Cholalic acid sodium salt

CAS Number: 206986-87-0
Empirical Formula (Hill Notation): C₂₄H₃₉NaO₅ · xH₂O
Molecular Weight: 430.55 (anhydrous basis)
EC Number: 206-643-5
MDL Number: MFCD00150749
Linear Formula: C₂₄H₃₉NaO₅ · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-C1254-25G	25 g	$97.80 1/EA	Add To Favorites
45-C1254-100G	100 g	$170.00 1/EA	Add To Favorites
45-C1254-500G	500 g	$793.00 1/EA	Add To Favorites
45-C1254-1KG	1 kg	$1340.00 1/EA	Add To Favorites
45-C1254-5KG	5 kg	$5170.00 1/EA	Add To Favorites

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This image depicts SKU: C1254-25G

Properties
Descriptions
Safety Info.
Basic Data

aggregation number	2-3
assay	≥99%
biological source	bovine and/or ovine bile
CMC	9-15 mM (20-25°C)
description	anionic
form	powder
HLB	18
InChI	1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
InChI key	MUVVIYFKOVLQHL-RCVKHMDESA-M
mol wt	micellar avg mol wt 900-1300
Quality Level	200
SMILES string	O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
solubility	water: 100 mg/mL, clear, colorless to light yellow
technique(s)	DNA purification: suitable
	RNA purification: suitable
	western blot: suitable

Application:	Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.
Biochem/physiol Actions:	Bile Salt
Features and Benefits:	• Suitable for Western blotting • Suitable for DNA and RNA purification • High purity product for research applications
General description:	Sodium cholate hydrate, a non-denaturing anionic detergent, plays a crucial role in biochemical research, particularly in protein solubilization and membrane permeabilization, making it essential for protein extraction and purification, especially when dealing with membrane proteins and protein complexes. Derived from cholic acid, a prevalent human bile acid, sodium cholate hydrate′s water solubility and its applications extend to investigating the effects of various substances on cell cultures, making it a versatile tool in laboratory research.
Other Notes:	For additional information on our range of Biochemicals , please complete this form .
Packaging:	1 kg in poly bottle
Packaging:	25, 100, 500 g in poly bottle
Packaging:	5 kg in poly drum

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99%
UNSPSC	12161900

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