Carboxypeptidase A−Agarose
SIGMA/C1261 - ammonium sulfate suspension, ≥6 units/mL packed gel, 25 °C, enzyme from bovine pancreas
Synonym: Carboxypolypeptidase; Peptidyl-L-amino-acid hydrolase
MDL Number: MFCD00130718
Product Type: Chemical
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| biological source | enzyme from bovine pancreas |
| form | ammonium sulfate suspension |
| matrix | beaded agarose |
| mol wt | ~35,250 |
| Quality Level | 200  |
| specific activity | ≥6 units/mL packed gel, 25 °C |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Carboxypeptidase as isolated from bovine pancreas glands is a metalloenzyme that contains 1 g atom of zinc per mole of protein. It catalyzes the hydrolysis of the carboxyl-terminal peptide bond in peptides and proteins. It is primarily specific to aromatic and hydrophobic side chains such as phenylalanine, tryptophan or leucine. The enzyme also exhibits esterase activity. It is inhibited by β-phenylpropionate and indole acetate. |
| Biochem/physiol Actions: | Carboxypeptidase A is attached covalently to agarose or aldehyde and is effective for immobilization studies. |
| General description: | Carboxypeptidase A-agarose product is prepared by the immobilization of carboxypeptidase A, originally isolated from the bovine pancreas, to activated 4% crosslinked beaded agarose. |
| Other Notes: | One unit will hydrolyze 1.0 μmole of hippuryl- |
| Physical form: | Suspension in 2.0 M (NH4)2SO4, pH 7 |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315 - H319 - H334 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42 |
| Safety Statements | 23-26-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥6 units/mL packed gel, 25 °C |
| Storage Temp. | 2-8°C |
| Enzyme Commission (EC) Number | 3.4.17.1 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |