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Chloro-APB hydrobromide

SIGMA/C130 - solid

Synonym: (±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide; (±)-SKF-82958 hydrobromide; 6-Chloro-N-allyl-SKF-38393 hydrobromide

CAS Number: 80751-65-1
Empirical Formula (Hill Notation): C19H20ClNO2 · HBr
Molecular Weight: 410.73
MDL Number: MFCD00069235
Linear Formula: C19H20ClNO2 · HBr
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C130-5MG 5 mg
 $196.00
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45-C130-25MG 25 mg
 $674.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C130-100MG

 

color tan
form solid
InChI 1S/C19H20ClNO2.BrH/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13;/h2-7,11,16,22-23H,1,8-10,12H2;1H
InChI key WLXGFAVTAAQOFH-UHFFFAOYSA-N
Quality Level 100 
SMILES string Br.Oc1cc2C(CN(CCc2c(Cl)c1O)CC=C)c3ccccc3
solubility aqueous base: unstable
  ethanol: soluble
  H2O: 3.7 mg/mL
storage temp. 2-8°C
Application: Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice.
Biochem/physiol Actions: Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats.
Disclaimer: Light sensitive
Packaging: 25, 100 mg in poly bottle
Packaging: 5 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352200

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