CGP-42112A

SIGMA/C160 - ≥95%, synthetic, solid

Synonym: N_α-Nicotinoyl-Tyr-(N_α-Cbz-Arg)-Lys-His-Pro-Ile

CAS Number: 127060-75-7
Empirical Formula (Hill Notation): C₅₂H₆₉N₁₃O₁₁
Molecular Weight: 1052.18
MDL Number: MFCD00133611
Linear Formula: C₅₂H₆₉N₁₃O₁₁
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-C160-1MG	1 mg	$302.00 1/EA		Add To Favorites
45-C160-5MG	5 mg	$1080.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
biological source	synthetic
color	white
form	solid
InChI	1S/C52H69N13O11/c1-3-32(2)43(50(73)74)64-48(71)42-17-11-25-65(42)49(72)41(27-36-29-56-31-59-36)62-46(69)39(60-47(70)40(26-33-18-20-37(66)21-19-33)61-44(67)35-14-9-22-55-28-35)15-7-8-23-57-45(68)38(16-10-24-58-51(53)54)63-52(75)76-30-34-12-5-4-6-13-34/h4-6,9,12-14,18-22,28-29,31-32,38-43,66H,3,7-8,10-11,15-17,23-27,30H2,1-2H3,(H,56,59)(H,57,68)(H,60,70)(H,61,67)(H,62,69)(H,63,75)(H,64,71)(H,73,74)(H4,53,54,58)/t32-,38-,39-,40-,41-,42-,43-/m0/s1
InChI key	UXGNARZDONUMMK-LRMQDCNJSA-N
Quality Level	200
SMILES string	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCCCNC(=O)[C@H](CCCNC(N)=N)NC(=O)OCc3ccccc3)NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)c5cccnc5)C(O)=O
storage temp.	−20°C

Amino Acid Sequence:	Tyr-Z-Arg-Lys-His-Pro-Ile
Application:	CGP-42112A has been used: • in the isolation of RNA from fibroblast-like synoviocytes from rheumatoid arthritis patients (RA-FLS) • to study its effects on the ERK2 phosphorylation in the cardiomyoblast cell line • as a stimulator of angiotensin II type 2 (AT2) receptor to study its effects on human regional hemodynamic responses mediated by AT2 receptors
Biochem/physiol Actions:	CGP-42112A is a potent angiotensin II type 2 receptor (AT2R) agonist.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	12352200

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