Monoclonal Anti-Cellular Retinoic Acid Binding Protein 1 antibody produced in mouse
SIGMA/C1608 - clone C-1, ascites fluid, buffered aqueous solution
Synonym: Anti-CRABP 1
MDL Number: MFCD02262690
Product Type: Chemical
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| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | C-1, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 16 kDa |
| Quality Level | 200  |
| shipped in | wet ice |
| should not react with | (chameleon), frog, goldfish |
| species reactivity | feline, turtle, monkey, rabbit, bovine, human, rat, chicken |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | P29762  |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
| Application: | Monoclonal Anti-Cellular Retinoic Acid Binding Protein 1 antibody produced in mouse is suitable for the following applications: • indirect ELISA • western blotting at a dilution of 1:1000 • immunofluorescence at a working dilution of 1:250 |
| Biochem/physiol Actions: | Cellular retinoic acid-binding protein 1 (CRABP1) is a prognostic marker for adenocarcinoma and clear cell carcinoma that exhibits chemo-resistance. It is a is a modulator of retinoic acid and plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 also functions as a tumor-suppressor in esophageal epithelium and its epigenetic silencing may play a pivotal role during esophageal carcinogenesis. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Cellular retinoic acid-binding protein 1 is a protein encoded by the CRABP1 gene in humans. It encodes a specific binding protein for a vitamin A family member. It is also referred as RBP5, CRABP, CRABPI and CRABP-I. |
| Immunogen: | performic acid oxidized CRABP 1, purified from bovine retina. |
| Physical form: | Solution in phosphate buffered saline containing 0.05% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |