Synonym: 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
CAS Number: 104615-18-1
Empirical Formula (Hill Notation): C13H8ClN5O
Molecular Weight: 285.69
MDL Number: MFCD01529897
Linear Formula: C13H8ClN5O
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white |
| form |
solid |
| InChI |
1S/C13H8ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h1-6H,(H2,15,16) |
| InChI key |
MSJODEOZODDVGW-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
Nc1nc2ccc(Cl)cc2c3nc(nn13)-c4ccco4 |
| solubility |
DMSO: >10 mg/mL |
| |
H2O: insoluble |
| storage temp. |
room temp |
| Application: |
CGS-15943 has been used as a non-selective adenosine receptor antagonist to study its effects on the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and hepatocellular carcinoma (HCC). It has also been used as a non-selective adenosine receptor antagonist to investigate the mechanism underlying adenosine inhibition on cholangiocarcinoma (CCA) cells. |
| Biochem/physiol Actions: |
CGS-15943 is a potent and non-selective adenosine receptor antagonist. It exhibits anti-carcinogenic and anti-apoptotic activity. |
| Packaging: |
25 mg in poly bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
room temp |
| UNSPSC |
12352202 |