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8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt

SIGMA/C240 - ≥98% (HPLC), solid

Synonym: Rp-8-CPT-cGMPS; Rp-8-[(4-Chlorophenyl)thio]-cGMPS triethylammonium salt; Rp-8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3′,5′-hydrogen phosphorothioate triethylammonium salt

CAS Number: 276696-61-8
Empirical Formula (Hill Notation): C16H15ClN5O6PS2 · C6H15N
Molecular Weight: 605.07
MDL Number: MFCD04037247
Linear Formula: C16H15ClN5O6PS2 · C6H15N
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C240-1MG 1 mg
 $619.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
biological source synthetic
color white
form solid
InChI 1S/C16H15ClN5O6PS2.C6H15N/c17-6-1-3-7(4-2-6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-8(27-14)5-26-29(25,30)28-11;1-4-7(5-2)6-3/h1-4,8,10-11,14,23H,5H2,(H,25,30)(H3,18,20,21,24);4-6H2,1-3H3/t8-,10-,11-,14-,29-;/m1./s1
InChI key KVOYZBYGWGWWTD-TXBWCVORSA-N
Quality Level 100 
SMILES string CCN(CC)CC.NC1=Nc2c(nc(Sc3ccc(Cl)cc3)n2[C@@H]4O[C@@H]5CO[P@@](O)(=S)O[C@H]5[C@H]4O)C(=O)N1
solubility H2O: 5 mg/mL
storage temp. −20°C
Biochem/physiol Actions: Rp-8-CPT-cGMP is a potent inhibitor of protein kinase G Ia, Ib, and type II.
Features and Benefits: This compound is featured on the PKA & PKG  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Other Notes: 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphorothioate, Rp Isomer triethylammonium salt is more cell permeable than Rp-cGMPS triethylamine.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 41106305

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