Cholesterol 5β,6β-epoxide
SIGMA/C2648 - ≥98%
Synonym: 5β,6β-Epoxycholestan-3β-ol
CAS Number: 4025-59-6
Empirical Formula (Hill Notation): C27H46O2
Molecular Weight: 402.65
MDL Number: MFCD00201258
Linear Formula: C27H46O2
Product Type: Chemical
| assay | ≥98% |
| form | powder |
| functional group | epoxy |
| InChI | 1S/C27H46O2/c1-17(2)7-6-8 |
| InChI key | PRYIJAGAEJZDBO-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| shipped in | ambient |
| SMILES string | [H][C@@]12[C@]([C@](CC[C@ |
| storage temp. | room temp |
| Application: | Cholesterol 5β,6β-epoxide was used to treat PC12 cells or HepG2 and Caco-2 cells to study the effects of cholesterol oxidation. |
| Biochem/physiol Actions: | Cholesterol 5β,6β-epoxide is an oxysterol produced as an oxidation product of cholesterol. Oxysterols are cytotoxic and induce death in monocytes, smooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation. |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 50 mg in poly bottle |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-68/20/21/22 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| Storage Temp. | room temp |
| UNSPSC | 12352211 |

