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Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated

SIGMA/C2901 - ≥95% (HPLC), powder

Synonym: CCK-8, non-sulfated

CAS Number: 25679-24-7
Empirical Formula (Hill Notation): C49H62N10O13S2
Molecular Weight: 1063.21
MDL Number: MFCD00076488
Linear Formula: C49H62N10O13S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C2901-1MG 1 mg
 $192.00
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assay ≥95% (HPLC)
form powder
InChI 1S/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)
InChI key OIXQINQYMGNCII-UHFFFAOYSA-N
Quality Level 200 
SMILES string CSCCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CC(O)=O)C(=O)NCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CCSC)C(=O)NC(CC(O)=O)C(=O)NC(Cc4ccccc4)C(N)=O
storage temp. −20°C
UniProt accession no. P06307 
Amino Acid Sequence: Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
Application: Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated has been used in the specificity testing against gastrin and pepsinogen I proteins.
Biochem/physiol Actions: Biologically inactive form of CCK-8; CCKB/gastrin receptor agonist that has no activity at the CCKA receptor.
Biochem/physiol Actions: Cholecystokinin (CCK) is a 115 amino acid preprohormone and a neurotransmitter. It exists in many isoforms. The octapeptide of CCK (CCK-8S) is the most abundant form. CCK is mapped to human chromosome 3p22.1. CCK interacts with receptors of the gastrointestinal tract and nervous system. Polymorphisms in the CCK is implicated in hallucinations in patients with Parkinson′s disease. CCK plays a key role in the activation of the calcineurin-regulated nuclear factor of activated T-cells (NFATs).
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 12352202

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