Collagen from human placenta
SIGMA/C3657 - Bornstein and Traub Type V (Sigma Type IX), powder
CAS Number: 9007-34-5
EC Number: 232-697-4
MDL Number: MFCD00130825
Product Type: Chemical
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| application(s) | detection |
| biological source | human placenta |
| form | powder |
| impurities | HIV, hepatitis B and hepatitis C, none detected |
| Quality Level | 200  |
| solubility | aqueous acid: soluble |
| storage temp. | 2-8°C |
| UniProt accession no. | P20908  |
| Analysis Note: | An SDS polyacrylamide gel electrophoresis test run under reducing conditions consistent with basement membrane collagen yields three major bands. |
| Disclaimer: | This product should be stored desiccated at -20°C, and will retain activity in these conditions for 3 years. |
| Other Notes: | All collagen molecules are composed of three polypeptide chains arranged in a triple helical conformation, with a primary structure that is mostly a repeating motif with glycine in every third position and proline or 4-hydroxyproline frequently preceding the glycine residue. |
| Other Notes: | Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Be wary of confusing Sigma-type designations with recognized collagen classification types. |
| Packaging: | 1, 5 mg in glass bottle |
| Preparation Note: | This product was prepared by a modification of the pepsin extraction and salt fractionation method of Niyibizi, C., et al., J. Biol. Chem., 259, 14170 (1984). It is an acid soluble collagen that can be dissolved in water with acetic acid added to pH 3.0 (5 mg/mL), yielding an opalescent, colorless solution. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |