Clindamycin hydrochloride
SIGMA/C5269 - lincosamide antibiotic
Synonym: (7S)
CAS Number: 21462-39-5
Empirical Formula (Hill Notation): C18H33ClN2O5S · HCl
Molecular Weight: 461.44
MDL Number: MFCD07793327
Linear Formula: C18H33ClN2O5S · HCl
Product Type: Chemical
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| form | powder or crystals |
| impurities | ≤13% |
| InChI | 1S/C18H33ClN2O5S.ClH/c1-5 |
| InChI key | AUODDLQVRAJAJM-XJQDNNTCSA |
| mode of action | protein synthesis | interferes |
| Quality Level | 200 ![]() |
| SMILES string | Cl.CCC[C@@H]1C[C@H](N(C)C |
| solubility | H2O: 50 mg/mL |
| storage temp. | 2-8°C |
| Application: | Clindamycin is used to study bacterial infections, such as group B streptococcal disease, bacterial resistance and plasma protein binding. |
| Application: | Used to study bacterial protein synthesis. |
| Biochem/physiol Actions: | Clindamycin hydrochloride is highly effective against anaerobic species. |
| Biochem/physiol Actions: | Clindamycin is a semi-synthetic, lincosamide antibiotic that is prepared from lincomycin. It inhibits bacterial protein synthesis by hydrogen bond interactions with the 23S rRNA component of the 50S ribosomal subunit thus inducing dissociation of the peptidyl-t-RNA complex. It has antibacterial activity against Gram-positive cocci and antiprotozoal activity against Taxoplasma. |
| General description: | Chemical structure: macrolide |
| Other Notes: | Antibacterial and antiprotozoal antibiotic of the lincosamide class. |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place. |
| Packaging: | 10 mg in poly bottle |
| Packaging: | 50, 100 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 51102829 |

